DMSO was given to female mice from age 10 weeks to see if lupus kidney injury could be reduced. Twenty mice were randomly assigned to saline or DMSO treatment groups and studies were done. These revealed nearly normal kidneys in 5/6 DMSO-treated mice whereas 4/8 controls had severe kidney inflammation. DMSO therefore appears capable of improving lupus kidney injury in mice. Milner LS, Amelioration of murine lupus nephritis by dimethylsulfoxide. Clin Immunol Immunopathol. 1987 Nov;45(2):259-67. PMID:3499277.

Auto-antibodies reactive with double-stranded DNA are a hallmark of systemic lupus erythematosus (SLE), but it is not fully understood how this contributes to various disease changes in lupus patients. We have have found that anti-DNA antibodies from the clear body fluids of lupus patients enhanced radical cleavage of DNA by hydroxyl radicals and this cleavage was inhibited by DMSO. Watanabe N, Enhancement of hydroxyl radical DNA cleavage by serum anti-dsDNA antibodies in SLE. Lupus, 1998;7(2):108-12. PMID:9541095.

Systemic lupus erythematosus patients sometimes present with pathologically confirmed lupus interstitial cystitis. Treatment with steroids has not been observed to be successful. Two patients are presented who were successfully treated by dimethyl sulfoxide (DMSO) being instilled into their bladders. Both patients remain symptom free years later. Sotolongo JR Jr, Successful treatment of lupus erythematosus cystitis with DMSO. Urology. 1984 Feb;23(2):125-7. PMID:6695477.

Directions for Use: As a minimum - Apply 4 to 6 sprays of 70% DMSO and 30% Aloe Vera morning and night to your torso or direct above any pain and rub in well. After application rub in a good quality moisturiser like "Natural Instinct" Natural Body Lotion to maintain skin condition. Optionally for a more powerful dose - Take 5ml (tsp) (3500mg) of 70% DMSO and 30% water in a glass of fresh juice or water every four to six hours.